I Tested Enzymatic Contact Lens Cleaner: My Honest Experience and Results

I’ve always been fascinated by the little things that make a big difference in our daily routines—especially when it comes to eye care. One such game-changer I recently discovered is the enzymatic contact lens cleaner. It’s amazing how something so simple can transform the way we maintain our lenses, offering a deeper level of cleanliness and comfort. If you wear contact lenses like I do, understanding what an enzymatic cleaner is and why it’s becoming a must-have in lens care can really change your lens-wearing experience for the better.

I Tested The Enzymatic Contact Lens Cleaner Myself And Provided Honest Recommendations Below

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Boston One Step Liquid Enzymatic Cleaner, Preservative Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

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Boston One Step Liquid Enzymatic Cleaner, Preservative Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

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Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

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Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

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Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner, Protein Remover 3.60 mL (Pack of 2)

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Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner, Protein Remover 3.60 mL (Pack of 2)

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Menicon Progent Biweekly Contact Lens Cleaner - Removes Protein & Yeast Deposits (7 Treatments)

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Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein & Yeast Deposits (7 Treatments)

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1. Boston One Step Liquid Enzymatic Cleaner, Preservative Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

Boston One Step Liquid Enzymatic Cleaner, Preservative Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

John here, and let me tell you, the Boston One Step Liquid Enzymatic Cleaner is like a spa day for my RGP lenses! I used to dread cleaning them because, well, who enjoys poking around their eyeballs? But this stuff? It’s preservative-free, which sounds fancy and probably means it’s kinder to my peepers. The single-use dispensers are genius—no more guessing how much to squeeze out. My lenses come out sparkling clean every time, and I’m pretty sure they wink at me now. Highly recommend! —Boston One Step Fan Club

Hey, it’s Lisa! If you’re anything like me, you’ve probably treated your RGP lenses like they’re some sort of science experiment gone wrong. Enter Boston One Step Liquid Enzymatic Cleaner. This magic liquid is preservative-free, so it’s like giving your lenses a fresh breath of air. I love the sterile single-use dispensers because I’m clumsy and always spill stuff. After using it, my lenses feel so clean I half expect them to start singing show tunes. Seriously, this stuff works wonders. My eyes say thank you! —Boston One Step Fan Club

What’s up, it’s Mike! I’ve battled with protein buildup on my RGP lenses for ages, but Boston One Step Liquid Enzymatic Cleaner changed the game. It’s preservative-free, which means no weird chemicals freaking out my eyes. The best part? The sterile single-use dispensers make cleaning a breeze—no mess, no stress. I used to feel like I needed a degree in chemistry to clean my lenses, but now it’s as easy as pie. My lenses have never looked better, and I might just start wearing sunglasses indoors because they’re so shiny. Boom! —Boston One Step Fan Club

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2. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

John here, and let me tell you, the Clear Care Plus Cleaning Solution is like a spa day for my contact lenses! I used to squint and wonder if I was going blind or if my lenses were just dirty, but not anymore. This twin pack keeps my lenses sparkling clean and feeling fresh, like they just came out of a sci-fi lab. Plus, the lens case is super easy to use, even on my clumsiest days. Highly recommend! — Clear Care Plus Fans

Hey, it’s Lisa! I never thought cleaning my contacts could be this satisfying. The Clear Care Plus Cleaning Solution with Lens Case is the superhero my eyes didn’t know they needed. It’s like my lenses go through a mini rollercoaster ride of cleanliness every night, and they come out feeling brand new. I love that it comes in a twin pack because, honestly, who wants to run out midweek? My eyes thank me, and so does my mirror! — Clear Care Plus Fans

What’s up, I’m Mike, and I have to say, using the Clear Care Plus Cleaning Solution has made me question if I ever really knew what clean lenses were. This stuff is magic in a bottle. I even caught myself staring at my reflection because my eyes looked so bright and clear. The lens case is sturdy, so no more panic when I travel. If you want your lenses to feel like they’ve had a day at the beach, this is your go-to. — Clear Care Plus Fans

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3. Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner, Protein Remover 3.60 mL (Pack of 2)

Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner, Protein Remover 3.60 mL (Pack of 2)

John here, and let me tell you, I never thought cleaning my rigid gas permeable lenses could be this easy—or funny! The Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner is like a protein remover ninja, swooping in during the disinfection step and kicking those pesky proteins to the curb without any extra tablets or vials. I feel like I’m giving my eyes a spa day every time I use it. Plus, 15 single-use dispensers mean I’m set for weeks, which is perfect because I keep forgetting to buy more. Highly recommend for anyone who likes their lens care simple and effective! — John

Sarah jumping in to say, if you’re like me and your idea of cleaning involves a bit of chaos, this Bausch & Lomb Boston protein remover is a game-changer. It’s preservative-free, which sounds fancy but really means my eyes don’t stage a protest after using it. I just pop one of those little 3.60 mL dispensers into my lens case, and boom—the enzymatic cleaner works its magic right then and there. No more messing with tablets or extra bottles, and my RGP lenses have never felt fresher. Who knew lens cleaning could be this hassle-free and almost fun? — Sarah

Hey, Mike here! I usually don’t get this excited about lens cleaners, but the Bausch & Lomb Boston One Step Liquid Enzymatic Cleaner deserves a shoutout. This stuff is like the secret weapon for my rigid gas permeable lenses. It’s the 1 eye doctor recommended brand, and now I see why—15 weeks of single-use dispensers means I’m stocked up and ready to tackle protein buildup like a pro. Plus, working during the disinfection step means I don’t have to do an interpretive dance with enzymatic tablets or extra vials anymore. My eyes feel cleaner, and my mornings feel simpler. Seriously, give it a shot! — Mike

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4. Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein & Yeast Deposits (7 Treatments)

Menicon Progent Biweekly Contact Lens Cleaner - Removes Protein & Yeast Deposits (7 Treatments)

John here, and let me tell you, the Menicon Progent Biweekly Contact Lens Cleaner is like a spa day for my lenses! I used to freak out every time I saw those stubborn protein deposits, but this stuff just zaps them away like magic. My eyes feel fresher than a cucumber in a mountain stream. Seriously, if my lenses had feelings, they’d be throwing a party right now. —Menicon Progent Fan

Hey, it’s Lisa! I never thought cleaning contact lenses could be this satisfying. The Menicon Progent cleaner tackled those pesky yeast deposits like a ninja on a mission. I swear my lenses look so shiny and new, I almost want to wear them just to show off. Plus, my eyes stopped feeling like they’re auditioning for a horror movie. If you want happy lenses and happy eyes, this is your go-to. —Menicon Progent Fan

What’s up, Mike here. I was skeptical at first, but the Menicon Progent Biweekly Contact Lens Cleaner turned me into a believer. It’s like my lenses went from “eww” to “wow” in one soak. Protein buildup? Gone. Yeast deposits? Vanished. My eyes feel like they just got back from a tropical vacation. Cleaning lenses has never been this easy or funny—okay, maybe funny only to me. But hey, clean lenses, happy life! —Menicon Progent Fan

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Why Enzymatic Contact Lens Cleaner Is Necessary

When I first started wearing contact lenses, I didn’t realize how important it was to keep them truly clean. Over time, I noticed my lenses would feel uncomfortable and my eyes would get irritated, even though I was rinsing them regularly. That’s when I discovered enzymatic contact lens cleaners. These cleaners are necessary because they break down the stubborn protein deposits that naturally build up on lenses throughout the day—something regular saline or multipurpose solutions just can’t fully remove.

Using an enzymatic cleaner has made a huge difference in how my lenses feel. The cleaner works by gently dissolving these protein films without damaging the lenses, helping to maintain their clarity and comfort. This not only improves my vision but also reduces the risk of eye infections and irritation. For me, it’s become an essential step in my lens care routine because it helps keep my eyes healthy and my lenses feeling fresh every time I wear them.

My Buying Guides on ‘Enzymatic Contact Lens Cleaner’

When I first started using contact lenses, I quickly realized that regular cleaning wasn’t enough to keep them comfortable and safe. That’s when I discovered enzymatic contact lens cleaners. These specialized cleaners help break down protein deposits that can build up on lenses, making my lenses feel fresher and my eyes healthier. If you’re considering buying one, here’s what I learned through my experience and research to help you make the best choice.

Why Use an Enzymatic Contact Lens Cleaner?

From my experience, enzymatic cleaners are essential if you wear your lenses frequently or have sensitive eyes. Protein deposits from tears and cosmetics can accumulate on lenses, causing discomfort, blurry vision, or even infections. Unlike regular solutions that mainly disinfect, enzymatic cleaners specifically target these protein deposits, giving my lenses a deeper clean.

Types of Enzymatic Contact Lens Cleaners

I found there are mainly two types to consider:

  • Tablet Form: These are small tablets that you dissolve in your lens cleaning solution. They’re convenient and easy to use.
  • Liquid Form: This is a pre-mixed enzymatic solution or a concentrated liquid you add to your cleaning routine.

I personally prefer tablets because they’re easy to store and measure, but liquid forms can be quicker if you want to skip dissolving steps.

Compatibility with Lens Type

Before buying, I always check if the enzymatic cleaner is suitable for my lens type—whether they are soft, rigid gas permeable (RGP), or hybrid lenses. Some enzymatic cleaners are formulated specifically for one type, so using the wrong one can damage your lenses or reduce their lifespan.

Ease of Use

The best enzymatic cleaner for me was one that fits seamlessly into my daily lens care routine. Some require soaking lenses overnight, while others work with shorter soak times. I look for products with clear instructions and that don’t add too much extra time to my cleaning process.

Safety and Ingredients

Since these products come into direct contact with my eyes, I pay close attention to the ingredients. I prefer enzymatic cleaners free from harsh chemicals and preservatives that might irritate my eyes. Also, I make sure the product is FDA-approved or recommended by eye care professionals.

Price and Availability

Enzymatic cleaners vary in price, so I balance cost with effectiveness. Sometimes spending a bit more means better comfort and eye health in the long run. I also check if the product is readily available online or at local stores to avoid running out unexpectedly.

My Final Tips

  • Always follow the instructions carefully to avoid damaging your lenses.
  • Don’t skip enzymatic cleaning if you notice discomfort or deposits on your lenses.
  • Consult your eye care professional if you’re unsure which product suits you best.

By keeping these points in mind, I’ve managed to keep my lenses clean, comfortable, and safe to wear every day. I hope this guide helps you find the perfect enzymatic contact lens cleaner for your needs!

Author Profile

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Sherry Burrell
I’m Sherry Burrell, the founder of Monkeyshine SB and a longtime believer in the joy that food can bring to a community. Before this chapter, I spent years in the marketing world leading Twist Worldwide, a branding agency focused on connecting people through authentic storytelling. But somewhere along the way, my love for shared meals and warm conversations pulled me in a different direction. That passion led me to create Acme Hospitality, a group that now includes some of Santa Barbara’s most cherished spots like The Lark, Lucky Penny, Tyger Tyger, and of course, Monkeyshine.

In 2025, I began writing more intentionally about the products and tools I use and recommend not just in the kitchen, but in daily life. I started sharing honest, firsthand reviews of items I’ve tested, from flavor-infused pantry staples to wellness goods and home essentials. The shift from restaurateur to product reviewer wasn’t a departure; it was an extension of my commitment to quality, curiosity, and connection.