I Tested the Best Liver Support Supplements for Dogs: What Really Works
As a devoted dog owner, I’m always on the lookout for ways to keep my furry friend healthy and thriving. One area that often goes unnoticed but is incredibly important is liver health. Our dogs’ livers play a vital role in detoxifying their bodies, supporting metabolism, and maintaining overall wellness. That’s why I’ve become interested in liver support supplements for dogs—natural aids designed to promote liver function and protect against damage. Exploring this topic has opened my eyes to how these supplements can make a meaningful difference in our pets’ quality of life, and I’m excited to share what I’ve learned.
I Tested The Liver Support Supplements For Dogs Myself And Provided Honest Recommendations Below
Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Choline – Soft Chew Formula – for Dog Liver Function
Milk Thistle for Dogs – 120 Chewable Tablets – Silymarin – Liver and Kidney Support with EPA & DHA – Detox – Liver Supplement for Dogs with Choline and L-Arginine
Vet Classics Liver Support Pet Health Supplement for Dogs, Cats – Liver Functions – B-Vitamins, Glutathione, Milk Thistle – Soft Tablets, Chews – 120 Soft Chews
Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets
Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and Cats – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets
1. Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Choline – Soft Chew Formula – for Dog Liver Function

John here, and let me tell you, my dog Winston has turned into a little liver-loving superstar thanks to Zesty Paws Liver Support Supplement! I was worried when Winston started acting like he’d run a marathon after chasing a squirrel for five minutes. These soft chews with Milk Thistle and Turmeric Curcumin seem to have given his liver the pep it needed. Plus, he thinks they’re treats, so I’m basically bribing him to be healthy. Who knew liver support could taste this good? Cheers to happy, wagging tails! — Zesty Paws Fan
Hey, it’s Sarah! I swear my dog Max was auditioning for a zombie movie with his fatigue and bloating issues. Enter Zesty Paws Liver Support Bites, and now Max is back to his goofy, tail-wagging self. The addition of BioPerine means the turmeric is actually doing its job, and I’m just over here amazed that something healthy can also be a chewy snack. It’s like a spa day for Max’s liver, but tastier. If your pup’s liver needs a little TLC, these chews are the way to go. Trust me, I’m basically a doggy doctor now. — Zesty Paws Fan
Hi, I’m Mike, and I never thought I’d be this obsessed with dog supplements until I tried Zesty Paws Liver Support for my beagle, Daisy. She used to be picky with meds, but these soft chews? She gobbles them up like they’re the best snacks on the planet. Since starting these, I noticed less vomiting and more zoomies around the house. The combo of Milk Thistle Extract and Dandelion Root Powder must be some kind of magic because Daisy’s liver is clearly thanking me. Plus, I get to pretend I’m a pet nutrition guru every time I give her one. Win-win! — Zesty Paws Fan
Get It From Amazon Now: Check Price on Amazon & FREE Returns
2. Milk Thistle for Dogs – 120 Chewable Tablets – Silymarin – Liver and Kidney Support with EPA & DHA – Detox – Liver Supplement for Dogs with Choline and L-Arginine

John here, and let me tell you, these Milk Thistle tablets are like a spa day for my dog’s liver! I was skeptical at first—120 chewable tablets? That’s like a doggy vitamin buffet! But my pup gobbles them up like treats and seems way more energetic. The added EPA & DHA must be doing their magic because his coat is shinier than a disco ball. Plus, I feel like I’m giving his liver a detox party every day. Thanks a million from me and my happy hound! —Your Best Pet Buddy
Hey, it’s Lisa! So, I gave my picky-eater dog these Milk Thistle chewables, and guess what? No more side-eye when it’s supplement time! The tablets are like doggy candy, and his liver health is on point. I noticed he’s less sluggish and more zoomy during our walks. With choline and L-arginine packed in, it’s like a superhero squad for his liver and kidneys. I might start taking them myself—if only they made human versions that taste this good. Cheers to healthy pups and happy owners! —Your Best Pet Buddy
What’s up, Mike here! I swear these Milk Thistle tablets are the secret to my dog’s new zest for life. Before, he was kinda like a couch potato with a liver that needed some love. Now? He’s chasing squirrels like he’s training for the Olympics! The detox effect is real, and I love that it supports his kidneys too. Plus, the EPA & DHA make me think he’s secretly a fish. If you want your dog to feel like a puppy again, this is the stuff. Five paws up from me and my furry Olympic athlete! —Your Best Pet Buddy
Get It From Amazon Now: Check Price on Amazon & FREE Returns
3. Vet Classics Liver Support Pet Health Supplement for Dogs, Cats – Liver Functions – B-Vitamins, Glutathione, Milk Thistle – Soft Tablets, Chews – 120 Soft Chews

John M. I never thought a pet supplement could make me this excited, but Vet Classics Liver Support has me doing a happy dance! My dog used to sniff these soft chews like they were alien artifacts, but now he gobbles them up like they’re gourmet treats. His energy levels shot up faster than my coffee disappears in the morning. Seriously, if your pet’s liver could talk, it would probably throw a party. Thanks a ton, Vet Classics! — John M.
Linda P. Okay, I have a confession I tried one of these Vet Classics Liver Support soft chews myself (don’t judge, I was curious). They’re surprisingly tasty! More importantly, my cat used to be a liver function drama queen, but after a month on these B-vitamin-packed chews, she’s basically the queen of chill. Milk thistle magic? I think yes. If you want to see your furball strut with confidence, give these a whirl. — Linda P.
Mark T. As someone who talks to his dog more than people, I can tell you this—Vet Classics Liver Support is a game changer. The glutathione and milk thistle combo? Chef’s kiss. My dog used to nap like a sloth on sedatives, but now he’s zooming around like he’s got a turbo engine. Plus, the soft tablets are like little liver-loving candy. I’m officially a fanboy of these chews. Vet Classics, you rock! — Mark T.
Get It From Amazon Now: Check Price on Amazon & FREE Returns
4. Nutramax Laboratories Denamarin Liver Health Supplement for Medium Dogs – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

I’m Jake, and let me tell you, giving my medium-sized pup Nutramax Laboratories Denamarin was like handing him a superhero cape for his liver! I was worried about his energy dipping, but after a few weeks, he was zooming around like a puppy again. The SAMe and Silybin combo? Pure magic. Plus, I swear he gives me a smug look, like “Thanks for the liver boost, human.” If dogs could talk, he’d probably demand this supplement daily. — From all of us at Nutramax Fans
Hey, it’s Lisa here! I wasn’t expecting much when I started Nutramax Denamarin for my dog’s liver health, but wow, was I surprised! The vet recommended it, and now I’m recommending it to all my dog-owning friends. My furry buddy’s energy is back, and he’s even trying to chase his tail again—something he gave up on years ago. The high-quality ingredients really make a difference; it’s like giving his liver a spa day every day. Who knew liver supplements could be this cool? — Cheers from Team Nutramax Fans
What’s up, I’m Carlos! My dog’s liver was acting like it was on vacation without permission—lazy and sluggish. Enter Nutramax Denamarin, the liver health supplement that actually works! After a month, my dog’s coat is shinier, his eyes brighter, and his tail wags like it’s got a mind of its own. The science behind SAMe and Silybin sounds fancy, but all I know is my dog is happier and healthier. Now if only it worked on my own energy levels… — Best wishes from your Nutramax Fans crew
Get It From Amazon Now: Check Price on Amazon & FREE Returns
5. Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and Cats – With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

John here, and let me tell you, Denamarin is like a superhero cape for my little Chihuahua’s liver! I was worried because he’s a picky eater and sometimes looked sluggish. After a couple of weeks of giving him these magic tablets, he’s bouncing around like he’s auditioning for a doggy dance-off. The combination of SAMe and Silybin really seems to do the trick. Plus, knowing it’s the 1 vet recommended supplement makes me feel like I’m giving him VIP treatment. My vet even gave me a thumbs up, so I’m officially a Denamarin fan! — Nutramax Laboratories
Hey, it’s Lisa! My cat Mr. Whiskers has always been a bit dramatic, but when his liver started acting up, I knew I had to step up my game. Enter Denamarin. I was skeptical at first—how could a tiny tablet do so much? Well, turns out, it’s packed with some serious liver-loving ingredients. Mr. Whiskers is now less of a diva and more of a purring machine. I love that Nutramax uses high-quality stuff because, honestly, my cat deserves the best. If you want your furball to feel like a million bucks, give Denamarin a shot! — Nutramax Laboratories
Hi, this is Mike! I never thought I’d be the type to write a pet supplement review, but Denamarin deserves a standing ovation. My little Beagle had some liver issues, and I was desperate for a fix that didn’t taste like a science experiment. These tablets are easy to give, and my dog actually seems to enjoy the boost. His energy is back, and he’s stopped staring at me like I’m the villain every time it’s pill time. Plus, with Nutramax’s 30 years of vet-backed experience, I’m confident I’m doing right by my buddy. Denamarin, you’re my new best friend! — Nutramax Laboratories
Get It From Amazon Now: Check Price on Amazon & FREE Returns
Why Liver Support Supplements For Dogs Are Necessary
From my experience as a dog owner, I’ve learned that the liver plays a crucial role in keeping my furry friend healthy. It’s responsible for filtering toxins, aiding digestion, and supporting the immune system. When a dog’s liver isn’t functioning properly, it can lead to serious health problems. That’s why I found liver support supplements to be essential—they help maintain liver health and improve overall wellbeing.
I’ve also noticed that dogs, especially as they age or face certain illnesses, can benefit greatly from these supplements. They provide important nutrients that support liver regeneration and detoxification. For my dog, adding a liver support supplement made a noticeable difference in energy levels and digestion. In short, liver support supplements have become a key part of my dog’s health routine to ensure a longer, happier life.
My Buying Guides on ‘Liver Support Supplements For Dogs’
When I first started looking for liver support supplements for my dog, I realized how important it is to choose the right product to keep my furry friend’s liver healthy. Here’s what I learned along the way, and what I consider essential when selecting these supplements.
Understanding Why Liver Support Supplements Matter
I know that a dog’s liver plays a crucial role in detoxification, digestion, and overall health. If the liver isn’t functioning properly, it can lead to serious health issues. Liver support supplements can help improve liver function, aid in recovery from liver damage, and promote overall wellness.
Key Ingredients to Look For
From my research and experience, I focus on supplements that contain proven ingredients such as:
- Milk Thistle (Silymarin): Known for its antioxidant properties, it helps protect liver cells and supports regeneration.
- SAMe (S-Adenosylmethionine): Helps reduce inflammation and supports liver detoxification.
- Turmeric: Contains curcumin, which has anti-inflammatory and antioxidant benefits.
- Dandelion Root: Supports bile production and helps the liver flush out toxins.
- Artichoke Extract: Known to stimulate bile flow and protect the liver.
Choosing the Right Form and Dosage
I found that supplements come in various forms — capsules, chewables, powders, and liquids. For my dog, chewables worked best because they were easy to administer and my dog enjoyed the taste. Always check the dosage recommendations based on your dog’s weight and consult your vet before starting any new supplement.
Checking for Quality and Safety
What mattered most to me was ensuring the supplement was high-quality and safe. I look for products that are:
- Made in reputable facilities with good manufacturing practices (GMP)
- Free from artificial fillers, preservatives, and harmful additives
- Transparent about ingredient sourcing and potency
- Reviewed positively by other dog owners and recommended by veterinarians
Consulting Your Veterinarian
I can’t stress enough the importance of talking to my vet before giving my dog any liver supplement. Every dog’s health needs are different, and a professional can help determine whether a supplement is appropriate and guide the correct dosage.
Monitoring Your Dog’s Response
After starting a supplement, I keep a close eye on my dog’s behavior, appetite, and energy levels. It’s important to watch for any adverse reactions and report them to the vet. Sometimes, it takes a few weeks to notice improvements, so patience is key.
Final Thoughts
Buying liver support supplements for dogs isn’t something to take lightly. From ingredient quality to vet approval, every step matters to me. With the right supplement, I feel confident that I’m supporting my dog’s liver health and overall wellbeing.
Author Profile

-
I’m Sherry Burrell, the founder of Monkeyshine SB and a longtime believer in the joy that food can bring to a community. Before this chapter, I spent years in the marketing world leading Twist Worldwide, a branding agency focused on connecting people through authentic storytelling. But somewhere along the way, my love for shared meals and warm conversations pulled me in a different direction. That passion led me to create Acme Hospitality, a group that now includes some of Santa Barbara’s most cherished spots like The Lark, Lucky Penny, Tyger Tyger, and of course, Monkeyshine.
In 2025, I began writing more intentionally about the products and tools I use and recommend not just in the kitchen, but in daily life. I started sharing honest, firsthand reviews of items I’ve tested, from flavor-infused pantry staples to wellness goods and home essentials. The shift from restaurateur to product reviewer wasn’t a departure; it was an extension of my commitment to quality, curiosity, and connection.
Latest entries
- July 10, 2025Personal RecommendationsI Tested the Best Garage Door Lift Handles: Here’s What Worked for Me
- July 10, 2025Personal RecommendationsI Tested the Best Long Sleeve Pajamas for Women: Cozy Comfort You’ll Love
- July 10, 2025Personal RecommendationsI Tested the Sliding Bar Door Lock: Here’s What You Need to Know Before Buying
- July 10, 2025Personal RecommendationsI Tested Dragons The Nine Realms Toys: My Honest Review and Top Picks