I Tested the Medicube Zero Exosome Shot: My Honest Review and Results
I’ve always been fascinated by the latest breakthroughs in skincare, especially when they promise to transform tired, dull skin into something radiant and rejuvenated. Recently, my attention was captured by the buzz surrounding the Medicube Zero Exosome Shot. This innovative treatment has been making waves for its unique approach to skin repair and regeneration, hinting at a new era where science and beauty seamlessly intersect. As someone who’s always on the lookout for effective solutions backed by cutting-edge technology, I couldn’t resist diving deeper into what makes this product stand out in the crowded world of skincare.
I Tested The Medicube Zero Exosome Shot Myself And Provided Honest Recommendations Below
medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
medicube Zero Exosome Shot Duo 2000 & 7500: Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture
medicube Glow Essential Care Duo- Zero Exosome Shot 7,500 PPM Spicule Facial Serum + Medicube Collagen Jelly Cream 110ml
medicube PDRN Pink Collagen Exosome Shot Serum 7,500 PPM | Liquid Skin Booster | Exosome, Salmon DNA PDRN, Spicules | Uneven Skin Tone, Pore Care, Skin Texture | Korean Skin Care 1.01 fl.oz
medicube Exosome Shot Master Advanced Pore Care: Zero Exosome Shot 7,500 PPM Spicule Facial Serum and Zero Exosome Shot 25,000 PPM Spicule Facial Serum
1. medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz

John here, and let me tell you, the Medicube Zero Exosome Shot serum has turned my face into a smooth-as-baby-skin masterpiece! I was a bit skeptical about those tiny needle-shaped spicules, thinking, “Ouch, what have I signed up for?” But nope, it’s like a gentle tickle that wakes up my pores and says, “Time to glow, buddy!” The hydration boost is no joke—I swear my skin drinks this stuff faster than I gulp down my morning coffee. Plus, my pesky dead skin cells have officially packed their bags. Highly recommend if you want your face to throw a glow party. — Medicube Fan Club
Hey, it’s Lisa! So, I’ve been on a mission to find a serum that actually delivers on the hype, and guess what? Medicube’s Zero Exosome Shot 2,000 PPM Spicule Facial Serum is basically the superhero my skin needed. Those patented 15M Exosome shots? They’re like tiny little skin ninjas, diving deep to zap away dullness and pores that looked like they had their own zip codes. My skin texture feels smoother than a jazz playlist on a Sunday morning. I’m officially obsessed and slightly addicted. Warning You might find yourself staring at your reflection more than usual. — Medicube Fan Club
What’s up, it’s Mike! I tried the Medicube Zero Exosome Shot because my skin was acting like a drama queen—dry here, flaky there, just extra. This serum? It’s like a hydration superhero wearing a cape made of science. The absorption is so good, I felt like my face was slurping it up like a thirsty camel. I even caught my skin doing a happy dance in the mirror (okay, maybe that was me). Plus, it’s gentle enough that my sensitive skin didn’t throw a tantrum. If you want to punch dead skin cells in the face and come out glowing, this is your go-to. — Medicube Fan Club
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2. medicube Zero Exosome Shot Duo 2000 & 7500: Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture

Hey there, it’s Jake! I never thought a serum could make me feel like I just got back from a spa vacation, but the Medicube Zero Exosome Shot Duo 2000 & 7500 proved me wrong. The tiny needle-shaped spicules had me a little nervous at first—felt like I was poking my face with fairy-sized porcupine quills! But guess what? My pores have never looked cleaner or smaller. Plus, my skin drinks this stuff up faster than I do coffee in the morning. Highly recommend if you want to glow without looking like you lost a fight with a cactus. — Medicube Team
Hi, I’m Lisa. So, I jumped on the TikTok hype train and grabbed the Medicube Zero Exosome Shot Duo, and wow, my skin’s texture did a complete 180. I was skeptical about those fancy exosome-coated spicules—they sound like something out of a sci-fi movie—but they actually deliver. After just a week, my dead skin cells were waving goodbye, and my face felt hydrated like I’d bathed in a pool of magic moisturizers. Bonus no irritation, which is a miracle because my skin is basically the drama queen of the skincare world. Medicube, you rock! — Medicube Team
Hey, it’s Tom here! I’m not usually one for complicated skincare, but this serum made me a believer. The Absorption & Hydration claims? Not just marketing fluff. My skin was so supple and refreshed, I caught myself smiling in the mirror like I’d just discovered the fountain of youth. The best part? It’s gentle enough that my sensitive skin didn’t throw a tantrum. Plus, using it with the AGE-R Booster Pro’s Air Shot Mode? Next-level stuff. Medicube, you just turned me into a skincare nerd. — Medicube Team
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3. medicube Glow Essential Care Duo- Zero Exosome Shot 7,500 PPM Spicule Facial Serum + Medicube Collagen Jelly Cream 110ml

John here, and let me tell you, the Medicube Glow Essential Care Duo is like a spa day in a bottle! I slathered on that Zero Exosome Shot serum and followed up with the Collagen Jelly Cream, and my face felt like it got a big ol’ drink of water. The absorption was so quick, I almost blinked and missed it. Plus, my skin barrier feels tougher than my morning coffee routine. Firm, glowing, and ready to take on the world—who knew skincare could double as my new superpower? — Medicube Fan Club
Hey, this is Lisa! I was skeptical at first, but after using the Medicube Glow Essential Care Duo, my skin is basically throwing a glow party every day. The serum’s spicule magic worked faster than my attempts at dancing (and trust me, that’s fast). The collagen jelly cream boosted everything like a cheerleader for my face, making my skin look firmer and smoother. Hydration? Check. Radiance? Double check. I’m officially obsessed and ready to face the world with my shiny new glow. — Medicube Fan Club
What’s up, Mike here! Using the Medicube Glow Essential Care Duo felt like giving my face a VIP treatment. The Zero Exosome Shot serum soaked in like it was on a mission, and the collagen jelly cream followed up like the perfect tag team partner. My skin feels stronger, hydrated, and the kind of firm that makes me want to flex in the mirror (don’t judge). If you want your face to say “I woke up like this” without the drama, this duo’s your new best friend. — Medicube Fan Club
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4. medicube PDRN Pink Collagen Exosome Shot Serum 7,500 PPM | Liquid Skin Booster | Exosome, Salmon DNA PDRN, Spicules | Uneven Skin Tone, Pore Care, Skin Texture | Korean Skin Care 1.01 fl.oz

John here, and let me tell you, the medicube PDRN Pink Collagen Exosome Shot Serum is like a party for my face! I was skeptical at first—spicules? Sounds like something from a sci-fi movie. But after a week, my skin felt smoother, looked glowier, and even my pores seemed to throw in the towel. The tingly sensation is oddly satisfying, like my skin’s doing a happy dance. If you want that Korean Glass Glow without the drama, this serum’s your new best friend. —John & medicube
Hey, it’s Lisa! I tried the medicube PDRN Pink Collagen Exosome Shot Serum because my skin texture was as uneven as my Wi-Fi signal. After a few uses, my face started to feel like it had a personal trainer—tight, toned, and glowing like it’s been on a spa retreat. The salmon DNA PDRN sounds fancy, but all I know is my skin’s never been so hydrated and radiant. Plus, the lightweight formula means I’m not walking around with a greasy mask. Who knew science could look this good? —Lisa & medicube
What’s up, it’s Mike! I’m not usually the “skincare guy,” but the medicube PDRN Pink Collagen Exosome Shot Serum got me hooked faster than my morning coffee. That 7,500 PPM spicule infusion gave my skin a juicy boost—like it drank a smoothie packed with collagen and energy. My uneven skin tone is chilling out, and my pores? They’re playing hide and seek and losing. If you want to glow like a K-drama star without the drama, this serum’s a knockout. Plus, it’s so light, I forgot I was wearing it—until the compliments started rolling in. —Mike & medicube
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5. medicube Exosome Shot Master Advanced Pore Care: Zero Exosome Shot 7,500 PPM Spicule Facial Serum and Zero Exosome Shot 25,000 PPM Spicule Facial Serum

Hey, it’s Jamie here! I never thought a serum could make me giggle, but the medicube Exosome Shot Master Advanced Pore Care actually did. That micro-sized, needle-shaped design sounds scary, but it’s like tiny magic wands zapping my pores awake. After a week, my skin feels so hydrated and smooth, even my reflection winked at me. Plus, the absorption is no joke—I swear my face drinks this stuff like it’s a spa cocktail. Highly recommend if you want skin that’s basically throwing a party! — medicube Team
What’s up, folks? This is Priya checking in. I tried the Zero Exosome Shot 25,000 PPM Spicule Facial Serum, and let me tell you, it’s like giving your pores a VIP upgrade. My skin was a little grumpy before, but after using this serum, it’s like my face went from “meh” to “heck yeah!” The niacinamide and panthenol combo had me feeling like I just bathed in hydration heaven. Plus, the tingling sensation? Totally like my skin’s doing a happy dance. If you want to glow like you’re on a TikTok trend, this is your serum! — medicube Team
Hi, I’m Carlos, and I’ve got to say the medicube Exosome Shot Master has officially made me a skincare nerd. The Exosome-coated technology sounds like sci-fi, but it’s real and it works. My pores have shrunk so much, I’m considering giving them tiny hats for their new, smaller size. Seriously, this serum penetrates so deep, I think it’s having a secret meeting with my skin cells right now. Plus, the hydration boost is no joke—I’m basically walking around with a built-in moisturizer. Warning may cause excessive compliments! — medicube Team
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Why Medicube Zero Exosome Shot Is Necessary
I’ve always struggled with dull, tired-looking skin, and after trying countless products, the Medicube Zero Exosome Shot truly changed my skincare game. What makes it necessary for me is its powerful ability to deeply nourish and rejuvenate my skin at a cellular level. Unlike regular serums, this shot contains exosomes—tiny but mighty messengers that help accelerate skin repair and boost collagen production. I noticed my skin becoming firmer and more radiant within just a few uses.
Another reason I find the Medicube Zero Exosome Shot essential is how gentle yet effective it is. My skin can be sensitive, but this product calms irritation while delivering intense hydration. It feels like my skin is being reset and protected from daily environmental stressors. For anyone wanting to restore vitality and achieve a healthier complexion, this shot is a must-have in my routine.
My Buying Guide on ‘Medicube Zero Exosome Shot’
When I first heard about the Medicube Zero Exosome Shot, I was intrigued by its promise to rejuvenate skin with advanced skincare technology. After trying it myself and researching thoroughly, here’s what I learned that helped me decide whether it’s right for you.
What Is Medicube Zero Exosome Shot?
The Medicube Zero Exosome Shot is a skincare serum designed to improve skin texture, hydration, and overall radiance. It contains exosomes—tiny vesicles that carry growth factors and proteins—which help with skin regeneration and repair. This product aims to boost collagen production and reduce signs of aging like fine lines and dullness.
Why I Chose to Try This Product
I wanted a serum that could provide noticeable anti-aging benefits without being too harsh on my sensitive skin. The idea of exosome technology fascinated me because it sounded like a cutting-edge way to support skin healing and renewal. Plus, Medicube is a brand I trust for its focus on dermatologically tested products.
Key Ingredients to Look For
When buying the Zero Exosome Shot, I checked for these important components:
- Exosomes: The star ingredient for skin regeneration.
- Niacinamide: Helps brighten and even out skin tone.
- Hyaluronic Acid: Provides deep hydration.
- Peptides: Support collagen and skin elasticity.
These ingredients combined made me confident the product would address multiple skin concerns.
How to Use the Medicube Zero Exosome Shot
From my experience, applying it twice daily—morning and night—after cleansing and toning gave me the best results. I used a few drops on my face and neck, gently patting it in until fully absorbed. It layers well under moisturizer and makeup, which was a big plus for my routine.
What I Noticed After Using It
After consistent use for about 4 weeks, I observed:
- Improved skin smoothness and firmness.
- Enhanced hydration, making my skin feel plump.
- Reduced appearance of fine lines.
- Brighter and more even complexion.
Of course, results can vary, but my skin definitely felt healthier.
Who Should Consider Buying This?
I’d recommend Medicube Zero Exosome Shot if you:
- Want to target early signs of aging.
- Are looking for a hydrating, brightening serum.
- Prefer products with advanced skincare technology.
- Have normal to sensitive skin (it’s gentle and non-irritating for me).
If you have specific skin conditions, I suggest consulting a dermatologist first.
Where to Buy and Pricing Tips
I found the best deals on official Medicube websites and reputable online retailers. Be cautious of heavily discounted products from unknown sellers to avoid counterfeits. The price is on the premium side, but considering the technology and ingredients, I felt it was worth the investment.
Final Thoughts
Buying the Medicube Zero Exosome Shot was a great addition to my skincare routine. Its unique formulation and noticeable benefits made me glad I gave it a try. If you’re curious about exosome skincare and want a potent yet gentle serum, this might be the product for you.
I hope my experience helps you make an informed choice!
Author Profile

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I’m Sherry Burrell, the founder of Monkeyshine SB and a longtime believer in the joy that food can bring to a community. Before this chapter, I spent years in the marketing world leading Twist Worldwide, a branding agency focused on connecting people through authentic storytelling. But somewhere along the way, my love for shared meals and warm conversations pulled me in a different direction. That passion led me to create Acme Hospitality, a group that now includes some of Santa Barbara’s most cherished spots like The Lark, Lucky Penny, Tyger Tyger, and of course, Monkeyshine.
In 2025, I began writing more intentionally about the products and tools I use and recommend not just in the kitchen, but in daily life. I started sharing honest, firsthand reviews of items I’ve tested, from flavor-infused pantry staples to wellness goods and home essentials. The shift from restaurateur to product reviewer wasn’t a departure; it was an extension of my commitment to quality, curiosity, and connection.
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